Frank G Holz Selected Research

Macular Degeneration (Age-Related Maculopathy)

10/2022	Patients with Neovascular Age-Related Macular Degeneration Requiring Intensive Intravitreal Aflibercept Treatment: An ARIES Post Hoc Analysis.
6/2022	Association Between Visual Acuity and Fluid Compartments with Treat-and-Extend Intravitreal Aflibercept in Neovascular Age-Related Macular Degeneration: An ARIES Post Hoc Analysis.
1/2022	Short-term real-world outcomes following intravitreal brolucizumab for neovascular AMD: SHIFT study.
1/2022	OCT Signs of Early Atrophy in Age-Related Macular Degeneration: Interreader Agreement: Classification of Atrophy Meetings Report 6.
1/2022	Fluid Control in Neovascular Age-Related Macular Degeneration with Brolucizumab: An Analysis of the HAWK and HARRIER Phase 3 Trials.
1/2022	Repeatability and Discriminatory Power of Chart-Based Visual Function Tests in Individuals With Age-Related Macular Degeneration: A MACUSTAR Study Report.
1/2022	EFFECT OF RETINAL THICKNESS VARIABILITY ON VISUAL OUTCOMES AND FLUID PERSISTENCE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Post Hoc Analysis of the HAWK and HARRIER Studies.
1/2022	North Carolina macular dystrophy shows a particular drusen phenotype and atrophy progression.
1/2022	Efficacy, durability, and safety of intravitreal faricimab up to every 16 weeks for neovascular age-related macular degeneration (TENAYA and LUCERNE): two randomised, double-masked, phase 3, non-inferiority trials.
1/2022	Intersession Repeatability of Structural Biomarkers in Early and Intermediate Age-Related Macular Degeneration: A MACUSTAR Study Report.

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Frank G Holz Research Topics

Disease

104	Macular Degeneration (Age-Related Maculopathy) 10/2022 - 02/2002
26	Atrophy 01/2022 - 02/2002
25	Telangiectasis (Telangiectasia) 12/2022 - 01/2007
25	Choroidal Neovascularization 01/2022 - 04/2002
24	Geographic Atrophy 01/2022 - 02/2002
22	Macular Edema 05/2021 - 11/2007
19	Disease Progression 01/2021 - 03/2008
15	Diabetic Retinopathy (Retinopathy, Diabetic) 02/2022 - 09/2007
15	Retinal Diseases 08/2019 - 02/2002
9	Pseudoxanthoma Elasticum (Gronblad Strandberg Syndrome) 10/2021 - 12/2009
9	Neoplasms (Cancer) 08/2021 - 11/2005
7	Vision Disorders (Hemeralopia) 01/2022 - 06/2010
7	Eye Diseases (Eye Disease) 01/2020 - 01/2006
7	Cataract (Cataracts) 10/2018 - 10/2008
6	Retinal Vein Occlusion 01/2017 - 12/2010
5	Melanoma (Melanoma, Malignant) 04/2022 - 01/2016
5	Inflammation (Inflammations) 01/2021 - 10/2015
5	Stargardt Disease 01/2021 - 04/2012
4	Retinal Perforations 07/2022 - 06/2010
4	Retinopathy of Prematurity (Retrolental Fibroplasia) 02/2022 - 11/2011
4	Glaucoma 02/2022 - 04/2011
4	Endophthalmitis (Ophthalmia) 01/2021 - 01/2016
4	Photophobia (Light Sensitivity) 01/2021 - 08/2007
4	Angioid Streaks 02/2020 - 07/2011
4	Phototoxic Dermatitis (Phototoxicity) 08/2016 - 08/2015
3	Central Serous Chorioretinopathy 11/2022 - 08/2010
3	Hereditary Nephritis (Alport Syndrome) 04/2022 - 03/2011
3	Ganglion Cysts (Ganglion) 01/2022 - 01/2015
3	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2022 - 09/2010
3	Retinal Degeneration 10/2021 - 01/2017
3	Hemorrhage 07/2020 - 10/2013
3	Retinal Detachment (Retinal Detachments) 06/2016 - 03/2004
3	Type 2 Diabetes Mellitus (MODY) 08/2015 - 01/2015
2	Proliferative Vitreoretinopathy 10/2022 - 02/2010
2	Keratoconus 04/2022 - 03/2020
2	Ataxia (Dyssynergia) 01/2022 - 01/2022
2	Retinitis Pigmentosa (Pigmentary Retinopathy) 12/2021 - 01/2019
2	Uveal melanoma 04/2020 - 10/2019
2	Cone-Rod Dystrophies 01/2020 - 01/2018
2	Epiretinal Membrane (Epiretinal Membranes) 12/2019 - 11/2013
2	Fibrosis (Cirrhosis) 10/2019 - 07/2011
2	Blindness (Hysterical Blindness) 02/2019 - 07/2008
2	Neoplasm Metastasis (Metastasis) 01/2019 - 11/2011
2	Scotoma (Scintillating Scotoma) 01/2019 - 07/2013
2	Epilepsy (Aura) 01/2017 - 12/2016
2	Pain (Aches) 05/2016 - 01/2011
2	Choroid Diseases 09/2014 - 04/2002
1	Polypoidal Choroidal Vasculopathy 11/2022

Drug/Important Bio-Agent (IBA)

102	Retinaldehyde (Retinal)IBA 12/2022 - 02/2002
29	Ranibizumab (Lucentis)FDA Link 01/2022 - 12/2007
24	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2022 - 11/2005
18	afliberceptIBA 10/2022 - 03/2013
15	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2010
15	LipofuscinIBA 01/2021 - 12/2002
10	Retinal Pigments (Pigments, Visual)IBA 10/2021 - 03/2004
8	brolucizumabIBA 01/2022 - 05/2016
8	Fluorescein (Funduscein)FDA LinkGeneric 01/2021 - 02/2003
8	Macular PigmentIBA 01/2019 - 06/2008
8	Bevacizumab (Avastin)FDA Link 01/2016 - 01/2007
5	Pharmaceutical PreparationsIBA 01/2021 - 01/2007
5	Proteins (Proteins, Gene)FDA Link 05/2020 - 03/2007
5	InflammasomesIBA 01/2019 - 08/2015
5	salicylhydroxamic acid (SHAM)IBA 10/2018 - 04/2011
4	Verteporfin (Visudyne)FDA Link 11/2022 - 12/2007
4	CollagenIBA 04/2022 - 10/2016
4	Therapeutic UsesIBA 01/2022 - 11/2011
4	Fluocinolone Acetonide (Capex)FDA LinkGeneric 05/2021 - 04/2011
3	1-phenyl-3,3-dimethyltriazene (PDT)IBA 11/2022 - 12/2007
3	sodium-binding benzofuran isophthalate (SBFI)IBA 02/2022 - 07/2020
3	Indocyanine Green (Cardio-Green)FDA LinkGeneric 01/2021 - 04/2002
3	lampalizumabIBA 01/2018 - 02/2014
3	Complement System Proteins (Complement)IBA 02/2014 - 07/2008
2	Silicone OilsIBA 01/2021 - 03/2004
2	Vascular Endothelial Growth FactorsIBA 01/2021 - 01/2020
2	Indicators and Reagents (Reagents)IBA 05/2020 - 08/2011
2	Deubiquitinating EnzymesIBA 05/2020 - 10/2019
2	Immunoglobulin FragmentsIBA 01/2020 - 05/2016
2	Formaldehyde (Formol)FDA Link 01/2019 - 01/2014
2	Hematoxylin (Haematoxylon)IBA 01/2018 - 01/2016
2	SteroidsIBA 01/2018 - 01/2017
2	Eosine Yellowish-(YS) (Eosin)IBA 01/2018 - 01/2016
2	Endothelial Growth FactorsIBA 01/2017 - 06/2010
2	Complement Factor D (Factor D)IBA 01/2017 - 02/2014
2	CytokinesIBA 10/2016 - 10/2015
2	LipidsIBA 05/2012 - 11/2011
2	Complement C3 (C3 Complement)IBA 04/2012 - 10/2009
2	Complement Factor H (Factor H)IBA 04/2012 - 10/2009

Therapy/Procedure

30	Lasers (Laser) 04/2022 - 02/2002
25	Therapeutics 01/2022 - 01/2006
8	Injections 10/2021 - 01/2010
8	Intravitreal Injections 12/2019 - 02/2010
6	Photochemotherapy (Photodynamic Therapy) 03/2015 - 02/2003
5	Light Coagulation 10/2018 - 03/2012
4	Vitrectomy 05/2021 - 05/2013
3	Transplantation 08/2019 - 01/2014
3	Lenses 11/2014 - 05/2013
2	Traction 12/2019 - 06/2010
2	Intraocular Injections 01/2016 - 05/2012
2	Plasmapheresis 12/2010 - 05/2009
2	Aftercare (After-Treatment) 06/2010 - 11/2005